Proteomics Approach to Identify Biomarkers in Neurodegenerative Diseases.

This chapter examines the use of proteomics in understanding pathogenesis and identifying possible biomarkers in a range of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and prion diseases. We have attempted to look at the neuroproteomic approach from a biomarker discovery point of view. Novel biomarkers can pave the way for new therapeutic targets and lead us to a better understanding of the pathogenesis involved in the neurodegenerative diseases.