Early Detection and Response to the First Imported Case of Zika Virus Disease - Hainan Province, China, 2025.

WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: Zika virus (ZIKV) is primarily transmitted by Aedes aegypti and Aedes albopictus. The Zika epidemics in China were primarily imported cases.

WHAT IS ADDED BY THIS REPORT?: This study documents the first laboratory-confirmed imported ZIKV case in Hainan Province, China. Phylogenetic analysis identified the Asian lineage, sharing 98.79% homology with a Thai strain.

WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: This investigation highlighted the need to strengthen the patriotic health campaign, reducing local mosquito-borne transmission risk at the source. Multi-pathogen (dengue/chikungunya/Zika) testing of a single sample by Haikou Customs enabled Zika detection, while timely cross-department notification and coordinated response effectively enhanced outbreak containment.