The Journal of infectious diseases · 2026
Risk of Hospitalization Related to Influenza A(H3N2) Virus Subclade K, Thailand, June-December 2025.
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Prasert Kriengkrai, Praphasiri Prabda, Ditsungnoen Darunee, Naosri Suriya, Phuygun Siripaporn, Nakphook Sutthichai, Yeesoonsang Seesai, Saiyarin Jatuporn, Thongpramul Nuttida, Panjangampatthana Apinya, Rolfes Melissa A, Davis William W, Montgomery Martha P, Akkapaiboon Okada Pilailuk, Bhunyakitikorn Wichan
Аннотация
Antigenically drifted influenza A(H3N2) subclade K viruses have contributed substantially to influenza burden since 2025, but their clinical severity is less well described. Using sentinel surveillance data from Thailand, we found no significant difference in the adjusted odds of hospitalization among those infected with subclade K versus other influenza viruses (adjusted odds ratio 1.06, 95% CI .67, 1.68). This approach to estimating hospitalization risk for an emerging influenza virus subclade using sentinel surveillance data could serve as a model for conducting future rapid assessments. Summary Using sentinel respiratory surveillance data from Thailand, this paper found no large, significant difference in hospitalization risk for patients infected with influenza A(H3N2) subclade K compared with other influenza viruses.