Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2026
Protective Effect of COVID-19 Vaccination on Post-Infection Visuospatial Deficits.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
da Silva Lucas Gomes, Fini Bruna Carmeni Di, Oliveira Jordano César Milagres, Rosa Daniela Valadão, Costa Danielle de Souza, de Miranda Débora Marques, Romano-Silva Marco Aurélio, de Paula Jonas Jardim
Аннотация
OBJECTIVE: COVID-19 has been associated with persistent cognitive deficits months after SARS-CoV-2 infection. Vaccination reduces severe disease, but its effect on post-infection cognition remains uncertain. We evaluated whether COVID-19 vaccination attenuates cognitive deficits after SARS-CoV-2.
METHODS: We assessed 237 adults with COVID-19 and 105 controls. Patients were grouped by vaccination status at infection (vaccinated n=87; unvaccinated n=150). The neuropsychological assessment covered language, visuospatial ability, visual memory, verbal memory, attention, executive functions, and working memory. Group differences were tested with Aligned Rank Transform ANOVA with Holm-corrected post hoc comparisons, adjusting for education.
RESULTS: Significant group differences were observed in visuospatial ability and visual memory, assessed with the Rey-Osterrieth Complex Figure Test (Copy, Immediate and Delayed Recall) (all p < 0.001). The vaccinated group outperformed the unvaccinated group (p = 0.022) on visuospatial performance. The Rey-Osterrieth Complex Figure Test Copy did not differ significantly among participants vaccinated with CoronaVac, AstraZeneca, or Pfizer.
CONCLUSIONS: The findings suggest that COVID-19 vaccination may mitigate post-infection visuospatial deficits, reinforcing the importance of immunization in preventing cognitive sequelae associated with the disease.
METHODS: We assessed 237 adults with COVID-19 and 105 controls. Patients were grouped by vaccination status at infection (vaccinated n=87; unvaccinated n=150). The neuropsychological assessment covered language, visuospatial ability, visual memory, verbal memory, attention, executive functions, and working memory. Group differences were tested with Aligned Rank Transform ANOVA with Holm-corrected post hoc comparisons, adjusting for education.
RESULTS: Significant group differences were observed in visuospatial ability and visual memory, assessed with the Rey-Osterrieth Complex Figure Test (Copy, Immediate and Delayed Recall) (all p < 0.001). The vaccinated group outperformed the unvaccinated group (p = 0.022) on visuospatial performance. The Rey-Osterrieth Complex Figure Test Copy did not differ significantly among participants vaccinated with CoronaVac, AstraZeneca, or Pfizer.
CONCLUSIONS: The findings suggest that COVID-19 vaccination may mitigate post-infection visuospatial deficits, reinforcing the importance of immunization in preventing cognitive sequelae associated with the disease.