Wiadomosci lekarskie (Warsaw, Poland : 1960) · 2026
Impact of hormonal disorders after surgical treatment of endocrine pathology on dermatologic status and the need for aesthetic rehabilitation.
СтатьяНазвание и аннотация: Перевод в очереди
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Tkachenko Rimma P, Ivanko Oleksandr V, Beshkovetska Yuliia I
Аннотация
OBJECTIVE: Aim: To evaluate the impact of postoperative hormonal disorders on dermatologic status and to determine the need for aesthetic rehabilitation in patients after surgical treatment of endocrine pathology.
PATIENTS AND METHODS: Materials and Methods: A prospective cohort study included 128 patients aged 19-76 years after endocrine surgery. The sample comprised 54 patients after thyroidectomy, 61 after parathyroidectomy, 3 after adrenalectomy, and 10 after combined procedures. Dermatologic examination, scar assessment, hormonal profiling, and quality-of-life evaluation using SF-36 and DLQI were performed. Quantitative variables were summarized as mean ± standard deviation or median and interquartile range; qualitative variables as absolute and relative frequencies. Comparative analysis used the chi-square test, relative risk (RR) with 95% confidence interval (CI), and Pearson correlation (r).
RESULTS: Results: Hormonal dysfunction was identified in 93 patients (72.7%). Dermatologic changes were found in 101 patients (78.9%), most commonly xerosis (50.0%), pathological scarring (40.6%), alopecia (28.9%), and pigmentation disorders (24.2%). Patients with hormonal imbalance had a significantly higher risk of dermatologic complications than those without endocrine dysfunction (88.2% vs 55.6%; RR = 1.59; 95% CI 1.21-2.08; p < 0.01). Aesthetic defects requiring correction were identified in 76 patients (59.4%). Scar severity correlated with impaired dermatology-specific quality of life (r = 0.61; p < 0.001).
CONCLUSION: Conclusions: Hormonal disorders after endocrine surgery are significantly associated with dermatologic complications and reduced quality of life. Integration of dermatologic surveillance and aesthetic rehabilitation into postoperative care is clinically justified.
PATIENTS AND METHODS: Materials and Methods: A prospective cohort study included 128 patients aged 19-76 years after endocrine surgery. The sample comprised 54 patients after thyroidectomy, 61 after parathyroidectomy, 3 after adrenalectomy, and 10 after combined procedures. Dermatologic examination, scar assessment, hormonal profiling, and quality-of-life evaluation using SF-36 and DLQI were performed. Quantitative variables were summarized as mean ± standard deviation or median and interquartile range; qualitative variables as absolute and relative frequencies. Comparative analysis used the chi-square test, relative risk (RR) with 95% confidence interval (CI), and Pearson correlation (r).
RESULTS: Results: Hormonal dysfunction was identified in 93 patients (72.7%). Dermatologic changes were found in 101 patients (78.9%), most commonly xerosis (50.0%), pathological scarring (40.6%), alopecia (28.9%), and pigmentation disorders (24.2%). Patients with hormonal imbalance had a significantly higher risk of dermatologic complications than those without endocrine dysfunction (88.2% vs 55.6%; RR = 1.59; 95% CI 1.21-2.08; p < 0.01). Aesthetic defects requiring correction were identified in 76 patients (59.4%). Scar severity correlated with impaired dermatology-specific quality of life (r = 0.61; p < 0.001).
CONCLUSION: Conclusions: Hormonal disorders after endocrine surgery are significantly associated with dermatologic complications and reduced quality of life. Integration of dermatologic surveillance and aesthetic rehabilitation into postoperative care is clinically justified.