Lipid Metabolism, Body Composition, and Diet in Acne Vulgaris: A Narrative Review.

Acne vulgaris is a common chronic inflammatory disorder of the pilosebaceous unit that is increasingly recognized as a condition linked to systemic metabolic disturbances. Growing evidence suggests that alterations in lipid metabolism, both in sebum composition and circulating lipid profiles, may play a key role in acne pathogenesis. This narrative review aims to summarize current knowledge on the relationships between lipid metabolism, body composition, diet, and acne. Acne vulgaris should be considered not only a dermatological condition but also a disorder with metabolic components. A deeper understanding of lipid-related mechanisms may support the development of more personalized and metabolically targeted therapeutic strategies.