Amyotrophic lateral sclerosis & frontotemporal degeneration · 2026
Strengthening care and research in ALS in Southeast Asia: a call for action.
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Fung Wai Yee, Agustini Sheila, Amornvit Jakkrit, Chai Josiah, Damian Ludwig F, Fadli Nurul, Pg Hj Mohd Yassin Dk Hjh Norazieda, Keovilayhong Southanalinh, Krishnan Dhayalen, Kulkantrakorn Kongkiat, Nguyen Tran Minh Duc, Ng Kay, Nghia Hoang T T, Ohnmar Ohnmar, Pengiran Tengah Dayangku Siti Nur Ashikin, Prado Mario, Remli Rabani, Rojana-Udomsart Arada, Le Tuan Tu Quoc, Yanuar Ahmad, Shahrizaila Nortina
Аннотация
In Southeast Asia (SEA), healthcare resources, infrastructure, and access to therapies in amyotrophic lateral sclerosis (ALS) remain limited compared to other parts of the Asia-Pacific region. Many SEA countries continue to face delays in diagnosis, fragmented care pathways, and limited representation in international research. Beyond health system challenges, ALS in SEA may also differ biologically. Emerging studies suggest that genetic variants and clinical phenotypes in Asian populations are not fully mirrored in Western cohorts. In this report, the authors summarize their country-specific background and status of care in ALS as well as their consensus on future strategies and actions. Key short- and long-term strategies are proposed, highlighting the critical need for regional collaboration and patient engagement to advance ALS care and research in the region.