Head & neck · 2026
Oncologic Outcomes and Treatment Feasibility of Transoral Carbon Dioxide Laser Microsurgery for Hypopharyngeal Tumors in Older Patients: A Retrospective Cohort Study.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Ono Takeharu, Chitose Shun-Ichi, Kurita Takashi, Sato Fumihiko, Fukahori Mioko, Sueyoshi Shintaro, Kawaguchi Toshihiko, Oka Tunehiro, Kuroiwa Taikai, Umeno Hirohito
Аннотация
BACKGROUND: We evaluated outcomes and complications of transoral CO2 laser microsurgery (TLM) for hypopharyngeal tumors and its feasibility in ≥ 75-year-old patients.
METHODS: We retrospectively reviewed 116 patients (without metastases) treated from February 2012 to October 2024 at our hospital. Oncologic outcomes were analyzed using Kaplan-Meier curves (110 patients; median follow-up: 5.3 years).
RESULTS: Five-year local control, disease-specific survival, and overall survival rates were 87.8%, 94.6%, and 85.6%, respectively. Postoperative dysphagia, aspiration pneumonia, pharyngolaryngeal edema, and vocal fold paralysis occurred in 9%, 4%, 3%, and 3% of patients, respectively; none required tracheostomy or surgical hemostasis under general anesthesia. The group with a history of head and neck irradiation had higher rates of dysphagia (p = 0.010) and aspiration pneumonia (p = 0.031) than those without. Differences between age groups were nonsignificant.
CONCLUSIONS: TLM appears safe and effective for older patients with appropriately selected hypopharyngeal tumors.
METHODS: We retrospectively reviewed 116 patients (without metastases) treated from February 2012 to October 2024 at our hospital. Oncologic outcomes were analyzed using Kaplan-Meier curves (110 patients; median follow-up: 5.3 years).
RESULTS: Five-year local control, disease-specific survival, and overall survival rates were 87.8%, 94.6%, and 85.6%, respectively. Postoperative dysphagia, aspiration pneumonia, pharyngolaryngeal edema, and vocal fold paralysis occurred in 9%, 4%, 3%, and 3% of patients, respectively; none required tracheostomy or surgical hemostasis under general anesthesia. The group with a history of head and neck irradiation had higher rates of dysphagia (p = 0.010) and aspiration pneumonia (p = 0.031) than those without. Differences between age groups were nonsignificant.
CONCLUSIONS: TLM appears safe and effective for older patients with appropriately selected hypopharyngeal tumors.