An Updated Review of Glucagon-Like Peptide-1 Receptor Agonists: Perioperative Implications, Guidance Statements, and Current Literature.

Glucagon-like peptide-1 receptor (GLP-1) agonist medications are becoming a commonly prescribed medication for patients undergoing surgical procedures. Perioperative management of this medication has become an important topic due to the known delayed gastric emptying leading to the potential for retained gastric contents elevating the risk for aspiration during anesthesia. This update will briefly review the history and mechanism of action of these medications. We will then pivot to discuss recent evidence and best practice strategies in managing perioperative patients on GLP-1 therapy.