Ni/Co-Catalyzed Reductive Coupling of Aldehydes and Ketones with Alkenyl Halides.

Reductive coupling of carbonyl compounds with alkenyl halides offers a direct route to substituted allylic alcohols. We report a cooperative Ni/Co catalytic system that combines nickel catalysis with cobalt phthalocyanine to couple aldehydes and ketones with alkenyl halides under mild, chromium-free conditions. The method accommodates less reactive ketones and displays representative functional-group tolerance.