Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion · 2026
Psychosocial and functional factors associated with depressive symptoms in older Mexican adults: A systematic review and meta-analysis.
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Jiménez Erick Alberto Medina, Quiroz Christian Oswaldo Acosta, Mimenza-Alvarado Alberto José, Flores Raquel García, Montelongo Iván Alejandro Torres, Mena Rafael Pizarro, Gutiérrez Lidia Antonia Gutiérrez, Aguilar-Navarro Sara Gloria
Аннотация
BACKGROUND: Evidence on factors associated with depressive symptoms in older Mexican adults remains dispersed.
OBJECTIVE: To synthesize sociodemographic, psychosocial, and functional factors associated with depressive symptoms among community-dwelling Mexican adults aged ≥60 years.
METHODS: Following PRISMA 2020, seven databases were searched for observational studies using validated depression instruments. Random-effects meta-analyses were conducted for factors with at least three comparable estimates; others were synthesized narratively.
RESULTS: Nineteen studies were included (six in the meta-analysis). Functional dependence in activities of daily living showed the strongest, most robust association with depressive symptoms (OR=2.26, 95% CI 1.95-2.63; I2=0%). Low educational attainment was directionally positive but imprecise (OR=2.47, 95% CI 0.42-14.50; I2=70%), and multimorbidity was inconclusive due to high heterogeneity (OR=1.77, 95% CI 0.77-4.07; I2=92%). Loneliness, elder abuse, food insecurity, poor self-rated health, and low social support showed suggestive associations but could not be pooled.
CONCLUSIONS: Functional dependence is the most consistent correlate of depressive symptoms in this population, supporting integrated depression screening and functional assessment. Longitudinal designs are needed to clarify causal pathways.
OBJECTIVE: To synthesize sociodemographic, psychosocial, and functional factors associated with depressive symptoms among community-dwelling Mexican adults aged ≥60 years.
METHODS: Following PRISMA 2020, seven databases were searched for observational studies using validated depression instruments. Random-effects meta-analyses were conducted for factors with at least three comparable estimates; others were synthesized narratively.
RESULTS: Nineteen studies were included (six in the meta-analysis). Functional dependence in activities of daily living showed the strongest, most robust association with depressive symptoms (OR=2.26, 95% CI 1.95-2.63; I2=0%). Low educational attainment was directionally positive but imprecise (OR=2.47, 95% CI 0.42-14.50; I2=70%), and multimorbidity was inconclusive due to high heterogeneity (OR=1.77, 95% CI 0.77-4.07; I2=92%). Loneliness, elder abuse, food insecurity, poor self-rated health, and low social support showed suggestive associations but could not be pooled.
CONCLUSIONS: Functional dependence is the most consistent correlate of depressive symptoms in this population, supporting integrated depression screening and functional assessment. Longitudinal designs are needed to clarify causal pathways.