Selective Dual Apical Surgery for Adjacent Immature and Mature Upper Incisors With a Large Periapical Lesion: A 4-Year Follow-Up Case Report.

Conservative dual apical surgery without conventional orthograde root canal treatment, as well as root-end resection/preparation/filing/sealing, can successfully manage large periapical lesions involving adjacent immature and mature teeth. This hypothesis-generating observation suggests bioactive root-end filling may reduce treatment burden in carefully selected cases, but further studies are needed.