Iron-Mediated C-H Hydroalkylation of Azauracils with Alkenes.

Fe(III)-mediated intermolecular C-H hydroalkylation of azauracils with alkenes has been developed under open-air conditions. Through this methodology, a number of alkylated azauracils were obtained in moderate to good yields by using NaBH4 as the hydrogen source at ambient temperature. Furthermore, this method allows the convenient installation of a deuterium atom into organic molecules.