Value in health regional issues · 2026
Valuing Health States: An EQ-5D-5L Value Set for Uzbekistan.
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Abduvalieva Nilufar, Mirkasimov Bakhrom, Rashitova Nilufar, Roudijk Bram, Rencz Fanni, Djalalova Dilfuza
Аннотация
OBJECTIVES: Developing countries, such as Uzbekistan, are becoming more interested in health technology assessments and economic evaluations. For the purpose of supporting cost-utility assessments, this study set out to develop an EuroQol 5-Dimension 5-Level (EQ-5D-5L) value set based on the preferences of the adult general population in Uzbekistan.
METHODS: In 2024, respondents from 5 regions in Uzbekistan were recruited based on two-stage quota sampling strategy to obtain a representative sample for age, gender and region. Using the EuroQol valuation protocol and standard quality control procedures, trained interviewers assisted participants in completing discrete choice experiment and composite time-trade-off tasks. Data were analyzed using heteroscedastic Tobit, conditional logit, and hybrid heteroscedastic Tobit models.
RESULTS: Overall, 1007 respondents from Uzbekistan were interviewed. With the chosen final value set (hybrid heteroscedastic Tobit), the estimated value for the worst health state (55555) was -0.740. Mobility (0.530) and pain/discomfort (0.377) showed the greatest disutility at their most severe levels, followed by self-care (0.353), anxiety/depression (0.258), and usual activities (0.222). The highest estimated value for an impaired health state was 0.955 for the 21111.
CONCLUSION: The study estimated EQ-5D-5L value set following a standardized protocol for Uzbekistan. To our knowledge, this is the first EQ-5D-5L value set for any Central Asian country. The value set will enable economic evaluations to reflect local preferences, inform health policy decisions and advance health outcomes research in Uzbekistan.
METHODS: In 2024, respondents from 5 regions in Uzbekistan were recruited based on two-stage quota sampling strategy to obtain a representative sample for age, gender and region. Using the EuroQol valuation protocol and standard quality control procedures, trained interviewers assisted participants in completing discrete choice experiment and composite time-trade-off tasks. Data were analyzed using heteroscedastic Tobit, conditional logit, and hybrid heteroscedastic Tobit models.
RESULTS: Overall, 1007 respondents from Uzbekistan were interviewed. With the chosen final value set (hybrid heteroscedastic Tobit), the estimated value for the worst health state (55555) was -0.740. Mobility (0.530) and pain/discomfort (0.377) showed the greatest disutility at their most severe levels, followed by self-care (0.353), anxiety/depression (0.258), and usual activities (0.222). The highest estimated value for an impaired health state was 0.955 for the 21111.
CONCLUSION: The study estimated EQ-5D-5L value set following a standardized protocol for Uzbekistan. To our knowledge, this is the first EQ-5D-5L value set for any Central Asian country. The value set will enable economic evaluations to reflect local preferences, inform health policy decisions and advance health outcomes research in Uzbekistan.