Wounds : a compendium of clinical research and practice · 2025
Topical timolol reduces the number of electrocauterization treatments required for treatment of pyogenic granulation after bromhidrosis surgery.
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Ho Wen-Tsao, Yang Chin-Yi
Аннотация
BACKGROUND: Pyogenic granulation is a common complication of bromhidrosis surgery, and multiple electrocauterization sessions are usually required to treat this condition.
OBJECTIVE: To investigate the effectiveness of topical timolol for improving electrocauterization outcomes for pyogenic granulation.
METHODS: The medical data of 20 patients who underwent bilateral bromhidrosis surgery followed by electrocauterization treatments for pyogenic granulation between January 2021 and December 2022 were retrospectively reviewed. The first 10 patients did not use topical timolol (non-timolol group), and the second 10 patients applied topical timolol maleate 0.5% drops twice daily (timolol group) after each session of electrocauterization. The total number of electrocauterization sessions received by the patients were compared between the 2 groups.
RESULTS: The number of electrocauterization sessions was significantly less in the timolol group compared with the non-timolol group (median [range]: 3.5 [2-5] vs 5.5 [2-9]; P = .007). There was no statistically significant difference in age and sex distribution between the groups.
CONCLUSION: Application of topical timolol twice daily is effective in decreasing the number of electrocauterization treatments required to treat pyogenic granulation after bromhidrosis surgery. Topical timolol can enhance wound healing and improve electrocauterization treatment outcomes.
OBJECTIVE: To investigate the effectiveness of topical timolol for improving electrocauterization outcomes for pyogenic granulation.
METHODS: The medical data of 20 patients who underwent bilateral bromhidrosis surgery followed by electrocauterization treatments for pyogenic granulation between January 2021 and December 2022 were retrospectively reviewed. The first 10 patients did not use topical timolol (non-timolol group), and the second 10 patients applied topical timolol maleate 0.5% drops twice daily (timolol group) after each session of electrocauterization. The total number of electrocauterization sessions received by the patients were compared between the 2 groups.
RESULTS: The number of electrocauterization sessions was significantly less in the timolol group compared with the non-timolol group (median [range]: 3.5 [2-5] vs 5.5 [2-9]; P = .007). There was no statistically significant difference in age and sex distribution between the groups.
CONCLUSION: Application of topical timolol twice daily is effective in decreasing the number of electrocauterization treatments required to treat pyogenic granulation after bromhidrosis surgery. Topical timolol can enhance wound healing and improve electrocauterization treatment outcomes.