Chronic pulmonary disease associated with an unusual dysgammaglobulinaemia.

A 26-year-old patient, subject to recurrent sino-pulmonary infections, with a previously unreported combination of immunological deficiencies is reported. There was a lack of serum immunoglobulin A, salivary immunoglobulin A, decreased serum immunoglobulin M and a deficiency of cellular immunity. It is suggested that this combination of deficits may represent a forme fruste of hereditary ataxia telangiectasia.