Medicine · 2025
Primary intracranial squamous cell carcinoma arising in epidermoid cysts: A case report and review of literature.
СтатьяКлинический случайОбзорНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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История · было → стало
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Lin Tao, Ding Ling
Аннотация
RATIONALE: A natural malignant transformation of intracranial epidermoid cysts (IECs) into squamous cell carcinomas (SCCs) is very rare, and the mechanism remains unclear. Due to its rarity, there is currently no consensus on the management of primary intracranial SCC (PISCC) at present.
PATIENT CONCERNS: A 55-year-old woman was with an IEC in the right cerebellopontine angle region in our report. Her neurological symptom deteriorated rapidly in the 1 month before the admission.
DIAGNOSES: The preoperative diagnosis was IEC. Postoperative pathological examination confirmed the presence of SCC arising within the background of an epidermoid cyst.
INTERVENTIONS: Following a comprehensive preoperative assessment, including physical examination, laboratory tests, and imaging studies, the patient underwent subtotal resection of the lesion. Postoperatively, a pathological examination was performed on the lesion tissue. A follow-up assessment of the patient was conducted 1 year later. Based on this case, we reviewed pertinent literature and preliminarily investigated the optimal management strategy for PISCC.
OUTCOMES: After treatment, the patient's dizziness resolved, and she was discharged in good condition. One year later, subsequent magnetic resonance imaging scans demonstrated no evidence of lesion recurrence.
LESSONS: In practice, it is prone to make a misdiagnosis or fail to reach a diagnosis for PISCCs due to the absence of specific clinical characteristics. Our clinicians should be more conscious of the necessity for timely diagnosis through targeted clinical strategies, which would result in more targeted treatment and a better prognosis.
PATIENT CONCERNS: A 55-year-old woman was with an IEC in the right cerebellopontine angle region in our report. Her neurological symptom deteriorated rapidly in the 1 month before the admission.
DIAGNOSES: The preoperative diagnosis was IEC. Postoperative pathological examination confirmed the presence of SCC arising within the background of an epidermoid cyst.
INTERVENTIONS: Following a comprehensive preoperative assessment, including physical examination, laboratory tests, and imaging studies, the patient underwent subtotal resection of the lesion. Postoperatively, a pathological examination was performed on the lesion tissue. A follow-up assessment of the patient was conducted 1 year later. Based on this case, we reviewed pertinent literature and preliminarily investigated the optimal management strategy for PISCC.
OUTCOMES: After treatment, the patient's dizziness resolved, and she was discharged in good condition. One year later, subsequent magnetic resonance imaging scans demonstrated no evidence of lesion recurrence.
LESSONS: In practice, it is prone to make a misdiagnosis or fail to reach a diagnosis for PISCCs due to the absence of specific clinical characteristics. Our clinicians should be more conscious of the necessity for timely diagnosis through targeted clinical strategies, which would result in more targeted treatment and a better prognosis.