Case reports in ophthalmological medicine · 2026
Atypical Epiretinal Proliferation in a Case of Tuberculosis Uveitis.
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Cömerter Doğukan, Düzgün Eyüp
Аннотация
INTRODUCTION: To report an unusual epiretinal proliferation (EP) case in tubercular serpiginous-like choroiditis.
CASE PRESENTATION: A 30-year-old female patient with a history of uveitis presented with blurry vision and floaters for 5 days. The visual acuities of the right and left eyes were 7/10 and 9/10, respectively. A slit lamp examination of the right eye showed moderate anterior uveitis with anterior chamber cells of 2+ and 1+ cells in the anterior vitreous. The left eye showed a posterior synechia at the inferior half of the pupil but no cells in the anterior chamber. Mild vitritis was observed in both eyes. A fundus examination revealed two atrophic punch-out lesions in the right eye and multiple pigmented chorioretinal scar-like lesions in the left eye. OCT showed cystoid macular edema in the right eye and a wide epiretinal proliferative membrane in the left eye. The immunocompetent patient had a family history of tuberculosis (TB) infection. The tuberculin skin test resulted in a ≥ 20-mm induration, and the QuantiFERON-TB Gold test was positive. The patient was started on topical and oral steroids. Additionally, anti-TB treatment was added, leading to a favorable outcome. Following treatment, signs of panuveitis showed resolution, and there was an improvement in vision symptoms.
CONCLUSIONS: To our knowledge, this may represent one of the first reported cases of EP associated with tubercular serpiginous-like choroiditis.
CASE PRESENTATION: A 30-year-old female patient with a history of uveitis presented with blurry vision and floaters for 5 days. The visual acuities of the right and left eyes were 7/10 and 9/10, respectively. A slit lamp examination of the right eye showed moderate anterior uveitis with anterior chamber cells of 2+ and 1+ cells in the anterior vitreous. The left eye showed a posterior synechia at the inferior half of the pupil but no cells in the anterior chamber. Mild vitritis was observed in both eyes. A fundus examination revealed two atrophic punch-out lesions in the right eye and multiple pigmented chorioretinal scar-like lesions in the left eye. OCT showed cystoid macular edema in the right eye and a wide epiretinal proliferative membrane in the left eye. The immunocompetent patient had a family history of tuberculosis (TB) infection. The tuberculin skin test resulted in a ≥ 20-mm induration, and the QuantiFERON-TB Gold test was positive. The patient was started on topical and oral steroids. Additionally, anti-TB treatment was added, leading to a favorable outcome. Following treatment, signs of panuveitis showed resolution, and there was an improvement in vision symptoms.
CONCLUSIONS: To our knowledge, this may represent one of the first reported cases of EP associated with tubercular serpiginous-like choroiditis.