Archives of physiology and biochemistry · 2026
Characteristics of 3D pCASL parameters in patients with moyamoya disease and their predictive value for cognitive function after revascularization surgery.
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Zhang Shiyuan, Ma Zhizhao, Liu Lijie, He Yeju, Li Xiaotong, Geng Zuojun
Аннотация
BACKGROUND: Moyamoya disease is a chronic progressive cerebrovascular disease, characterised by stenosis or occlusion of the ends and branches of bilateral internal carotid arteries, accompanied by the formation of abnormal vascular networks at the base of the skull.
PURPOSE: Through non-invasive detection techniques such as magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI). It provides important basis for clinical treatment.
METHOD: This study aims to explore the characteristics of three-dimensional pseudo-continuous arterial spin labelling (3D-pCASL) parameters in patients with moyamoya disease and their predictive value for the improvement of cognitive function after revascularization, and to investigate the potential application value of 3D-pCASL parameters in evaluating neuronal injury and predicting the improvement of postoperative cognitive function.
CONCLUSION: This study further confirmed the application value of 3D-pCASL parameters in the examination of neuronal injury and the prediction of postoperative cognitive function improvement, providing an objective imaging basis for the early clinical identification of patients.
PURPOSE: Through non-invasive detection techniques such as magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI). It provides important basis for clinical treatment.
METHOD: This study aims to explore the characteristics of three-dimensional pseudo-continuous arterial spin labelling (3D-pCASL) parameters in patients with moyamoya disease and their predictive value for the improvement of cognitive function after revascularization, and to investigate the potential application value of 3D-pCASL parameters in evaluating neuronal injury and predicting the improvement of postoperative cognitive function.
CONCLUSION: This study further confirmed the application value of 3D-pCASL parameters in the examination of neuronal injury and the prediction of postoperative cognitive function improvement, providing an objective imaging basis for the early clinical identification of patients.