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DOI 10.1242/dev.204555

Медицинская библиотека · Development (Cambridge, England) · 2025

Multi-modal refinement of the human heart atlas during the first gestational trimester.

De Bono Christopher, Xu Yichi, Kausar Samina, Herbane Marine, Humbert Camille, Rafatov Sevda, Missirian Chantal, Moreno Mathias, Shi Weiyang, Gitton Yorick, Lombardini Alberto, Vanzetta Ivo, Mazaud-Guittot Séverine, Chédotal Alain, Baudot Anaïs, Zaffran Stéphane, Etchevers Heather C

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Аннотация

PURPOSE: To describe the clinical role of swept-source anterior segment optical coherence tomography in extraocular muscle imaging in various strabismic conditions.

STUDY

DESIGN

Prospective observational study.

PARTICIPANTS

A total of 1104 extraocular muscles of 150 subjects were imaged. Normal eyes (640 muscles), eyes undergoing re-operation (240 muscles), paralytic strabismic eyes (16 muscles), non-paralytic strabismic eyes (20 muscles), post-traumatic strabismic eyes (64 muscles), eyes with thyroid disease (64 muscles), and other atypical cases (60 muscles) were imaged. In all cases, up to four recti muscles were evaluated in a given eye depending on the need.

RESULTS

The mean age was 38.15 ± 16.25 years. Overall, muscle insertion was identified in over 90% of the subjects. Apart from normal muscles (n = 860, 93.68%), the location was identified in previously operated eyes (n = 54, 90%), in traumatic muscle slippage (n = 2, 11.11%), in ocular coat ectasia (n = 11, 91.66%), in thyroid muscle hypertrophy, in operated scleral fixated intraocular lens with strabismus, and other challenging cases. In all circumstances, clinically useful information was obtained from the anterior 4-14 millimetres of the rectus muscle, which in turn helped in active surgical planning and overall management.

CONCLUSION

The SS-ASOCT with its wider and deeper scanning abilities was able to locate the extraocular muscle insertion in a variety of strabismic conditions. Therefore, this tool can be used in the preoperative periods for optimal surgical planning and management.

Для цитирования: De Bono Christopher, Xu Yichi, Kausar Samina, Herbane Marine, Humbert Camille, Rafatov Sevda, Missirian Chantal, Moreno Mathias, Shi Weiyang, Gitton Yorick, Lombardini Alberto, Vanzetta Ivo, Mazaud-Guittot Séverine, Chédotal Alain, Baudot Anaïs, Zaffran Stéphane, Etchevers Heather C. Multi-modal refinement of the human heart atlas during the first gestational trimester.. Development (Cambridge, England). 2025. DOI: 10.1242/dev.204555.

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