Internal medicine (Tokyo, Japan) · 2024
Ectopic Adrenocorticotropic Hormone Syndrome due to Pancreatic Neuroendocrine Carcinoma.
СтатьяКлинический случайНазвание и аннотация: Перевод в очереди
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Kawanishi Aya, Deguchi Ryuzo, Ito Ayano, Ueda Takashi, Tsuruya Kota, Arase Yoshitaka, Shirataki Yoshihiro, Kodama Toshiki, Morimachi Masashi, Kagawa Tatehiro
Аннотация
A 55-year-old woman presented to her primary care physician with facial and lower leg edema. After being referred to our hospital because of hypothyroidism and hypokalemia on blood tests, she also had elevated adrenocorticotropic hormone (ACTH) and cortisol levels, but a dexamethasone suppression test showed no cortisol suppression. Ectopic ACTH syndrome due to pancreatic neuroendocrine carcinoma (PNEC) was suspected. endoscopic ultrasound-guided fine-needle aspiration was performed, and a histopathological examination of the obtained specimen revealed multiple liver metastases of the PNEC. Imaging after etoposide and cisplatin therapy showed cystic changes in the primary lesions and shrinkage of the liver metastases, and the ACTH levels were within the normal range.