Journal of cosmetic dermatology · 2025
Comparison of the Efficacy of 1064- and 730-nm Picosecond Lasers for Acquired Dermal Melanocytosis.
СтатьяСравнительное исследованиеНазвание и аннотация: Перевод в очереди
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Takaya Kento, Kishi Kazuo
Аннотация
BACKGROUND: Acquired dermal melanocytosis (ADM) is a pigmentary lesion caused by melanocytes in the dermis. These conditions are refractory, and a consensus on treatment remains elusive.
AIMS: To compare the efficacy of 730- and 1064-nm picosecond lasers in the treatment of ADM and to supplement the comparison with a literature review.
PATIENTS: We retrospectively examined patients who underwent picosecond laser therapy between April 2021 and February 2024. Treatments were performed three times with spot irradiation using a 730-nm laser (3-mm spot, 1.7-1.8 J/cm2; or 2-mm spot, 2.5-3.25 J/cm2) and a 1064-nm laser (3-mm spot, 3.1-4.0 J/cm2). Two months after each procedure, patient satisfaction was evaluated using questionnaires, macroscopic findings were assessed using photographs, and melanin accumulation was analyzed using skin analysis software. Evaluations were conducted on a 4-point scale (excellent, good, fair, and poor), with good or higher considered effective.
RESULTS: Seventy-eight and 83 patients were assigned to the 730- and 1064-nm groups, respectively. After three sessions, the 730-nm group exhibited superior outcomes in terms of subjective symptoms (patient satisfaction), objective findings, and software analysis improvements. The incidence of hyperpigmentation was 15.4% in the 1064-nm group and 14.5% in the 730-nm group, with no significant differences observed in the rates of other complications.
CONCLUSIONS: The use of a 730-nm picosecond laser, which possesses high melanin selectivity, relatively deep penetration, and a short pulse width, suggests a potentially more effective treatment for ADM, compared to the effects of the conventional 1064-nm wavelength, without increasing complications.
AIMS: To compare the efficacy of 730- and 1064-nm picosecond lasers in the treatment of ADM and to supplement the comparison with a literature review.
PATIENTS: We retrospectively examined patients who underwent picosecond laser therapy between April 2021 and February 2024. Treatments were performed three times with spot irradiation using a 730-nm laser (3-mm spot, 1.7-1.8 J/cm2; or 2-mm spot, 2.5-3.25 J/cm2) and a 1064-nm laser (3-mm spot, 3.1-4.0 J/cm2). Two months after each procedure, patient satisfaction was evaluated using questionnaires, macroscopic findings were assessed using photographs, and melanin accumulation was analyzed using skin analysis software. Evaluations were conducted on a 4-point scale (excellent, good, fair, and poor), with good or higher considered effective.
RESULTS: Seventy-eight and 83 patients were assigned to the 730- and 1064-nm groups, respectively. After three sessions, the 730-nm group exhibited superior outcomes in terms of subjective symptoms (patient satisfaction), objective findings, and software analysis improvements. The incidence of hyperpigmentation was 15.4% in the 1064-nm group and 14.5% in the 730-nm group, with no significant differences observed in the rates of other complications.
CONCLUSIONS: The use of a 730-nm picosecond laser, which possesses high melanin selectivity, relatively deep penetration, and a short pulse width, suggests a potentially more effective treatment for ADM, compared to the effects of the conventional 1064-nm wavelength, without increasing complications.