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Войти в исследования Journal of mood and anxiety disorders · 2026
Comparisons of anxiety, depression, and general health and well-being in a gender diverse sample of LGBTQ+ adults.
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Moitra Ethan, Gonzalez Nicole A, Kunicki Zachary J, Fenn Natalie, Cancilliere Mary Kathryn, Arnold Trisha
Аннотация
BACKGROUND: People who identify as LGBTQ+ report significantly higher rates of mental illness compared to cisgender, heterosexual populations. Transgender and non-binary (TNB) individuals show substantial mental health challenges when compared to non-LGBTQ+ people. However, few studies have explored TNB mental health compared to cisgender sexual minority individuals within a clinical LGBTQ+ sample.
METHOD: This observational study examined differences in anxiety, depression, general health and well-being, and psychiatric diagnoses in a sample of adults who identified as LGBTQ+ according to their self-reported gender identity (TNB vs. cisgender). The sample consisted of 100 TNB and 139 cisgender sexual minority adults (n = 239 total). Participants were in their early to mid-30s, mostly identified as non-Hispanic/Latino White, and were employed. Self-report measures of anxiety, depression, general health/well-being, and interviewer-administered measures of anxiety, depression, and psychiatric diagnoses were used.
RESULTS: After adjusting for age, ethnicity, and race in an analysis of covariance (ANCOVA) model, compared to cisgender sexual minority individuals, participants who identified as TNB demonstrated significantly worse anxiety (self-report: d=0.33; interview: d=0.56), depression (self-report: d=0.27; interview: d=0.25), and general health/well-being (d=-0.34). TNB individuals were also significantly more likely to meet criteria for depressive or anxiety disorders (OR=2.19, 95%CI: 1.17, 4.08, p = .014).
CONCLUSIONS: This is among the first studies to compare mental health and well-being within a LGBTQ+ adult sample according to individuals' gender identity. Results indicate that people who identify as TNB have a particularly high mental health burden, underscoring the importance of careful screening and tailored interventions for this subgroup.
METHOD: This observational study examined differences in anxiety, depression, general health and well-being, and psychiatric diagnoses in a sample of adults who identified as LGBTQ+ according to their self-reported gender identity (TNB vs. cisgender). The sample consisted of 100 TNB and 139 cisgender sexual minority adults (n = 239 total). Participants were in their early to mid-30s, mostly identified as non-Hispanic/Latino White, and were employed. Self-report measures of anxiety, depression, general health/well-being, and interviewer-administered measures of anxiety, depression, and psychiatric diagnoses were used.
RESULTS: After adjusting for age, ethnicity, and race in an analysis of covariance (ANCOVA) model, compared to cisgender sexual minority individuals, participants who identified as TNB demonstrated significantly worse anxiety (self-report: d=0.33; interview: d=0.56), depression (self-report: d=0.27; interview: d=0.25), and general health/well-being (d=-0.34). TNB individuals were also significantly more likely to meet criteria for depressive or anxiety disorders (OR=2.19, 95%CI: 1.17, 4.08, p = .014).
CONCLUSIONS: This is among the first studies to compare mental health and well-being within a LGBTQ+ adult sample according to individuals' gender identity. Results indicate that people who identify as TNB have a particularly high mental health burden, underscoring the importance of careful screening and tailored interventions for this subgroup.