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Войти в исследования Frontiers in medicine · 2026
A rare case of adenoma of the nonpigmented ciliary epithelium managed with a triple procedure: a case report.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Jin Yangyang, Zhou Lujia, Zhang Qiuyang, Xu Xiangzhong, Ding Xiyan
Аннотация
INTRODUCTION: Adenoma of the non-pigmented ciliary epithelium (ANPCE) is a rare intraocular tumor that is frequently misdiagnosed due to its concealed location and non-specific presentation. This report describes the diagnostic challenges of ANPCE and presents a novel "triple procedure" surgical approach that integrates partial lamellar sclerouvectomy (PLSU) with concurrent phacoemulsification and intraocular lens (IOL) implantation.
CASE PRESENTATION: A 39-year-old Asian woman presented with a two-month history of progressive visual decline in the left eye, which had been initially misdiagnosed as a cataract at a referral hospital. Slit-lamp examination revealed a mass posterior to the iris at the 10-11 o'clock position. Multimodal imaging, including ultrasound biomicroscopy (UBM) and magnetic resonance imaging (MRI), demonstrated a ciliary body lesion. An incisional biopsy with immunohistochemical analysis confirmed the diagnosis of ANPCE. The patient subsequently underwent localized tumor resection via PLSU combined with phacoemulsification and IOL implantation. Postoperatively, the best-corrected visual acuity (BCVA) improved to 20/22 (0.9), and no recurrence was observed during follow-up.
CONCLUSION: Unexplained unilateral cataract warrants meticulous slit-lamp and UBM evaluation to exclude occult ciliary body tumors. A staged diagnostic approach may reduce iatrogenic risk, while a triple procedure can achieve complete tumor clearance and restore visual function.
CASE PRESENTATION: A 39-year-old Asian woman presented with a two-month history of progressive visual decline in the left eye, which had been initially misdiagnosed as a cataract at a referral hospital. Slit-lamp examination revealed a mass posterior to the iris at the 10-11 o'clock position. Multimodal imaging, including ultrasound biomicroscopy (UBM) and magnetic resonance imaging (MRI), demonstrated a ciliary body lesion. An incisional biopsy with immunohistochemical analysis confirmed the diagnosis of ANPCE. The patient subsequently underwent localized tumor resection via PLSU combined with phacoemulsification and IOL implantation. Postoperatively, the best-corrected visual acuity (BCVA) improved to 20/22 (0.9), and no recurrence was observed during follow-up.
CONCLUSION: Unexplained unilateral cataract warrants meticulous slit-lamp and UBM evaluation to exclude occult ciliary body tumors. A staged diagnostic approach may reduce iatrogenic risk, while a triple procedure can achieve complete tumor clearance and restore visual function.