Klinische Monatsblatter fur Augenheilkunde · 2018
[Correlation of Quantitative Metamorphopsia Measurement and Central Retinal Thickness in Diabetic Macular Edema and Age-Related Exsudative Macular Degeneration].
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Claessens Daniela, Schuster Alexander K
Аннотация
BACKGROUND: Amsler Test is the standard used to detect metamorphopsia. To develop a tool to quantitatively measure and monitor metamorphopsia, the computer-based test "AMD - A Metamorphopsia Detector®" was developed. This study was performed to examine the correlation of metamorphopsia index (MI) and central retinal thickness (CRT) in exsudative age-related macular degeneration (AMD) and diabetic macular edema (DME).
MATERIAL AND METHODS: Sixty-six eyes of 66 patients, DME: 19 (11 males, 8 females; age 42 - 76); AMD: 47 (13 male, 34 female; age 56 - 93) were included in this convenient sample study and classified as having or not having macular edema (central 500 µm, Cirrus HD-OCT). Best corrected monocular distance visual acuity (BCVA), Amsler Test, Metamorphopsia Index of AMD - A Metamorphopsia Detector, binocular ophthalmoscopy, central retinal thickness (SD-OCT) and fluorescein angiography, if necessary, were performed. Correlation of central retinal thickness and metamorphopsia index was evaluated by Spearman correlation.
RESULTS: Mean BCVA (logMAR) was 0.27 (SD 0.3) in DME and 0.29 (SD 0.2) in AMD. Spearman's rho as a measure for correlation between CRT and MI was 0.88 (p < 0.001) in DME and 0.56 (p < 0.001) in AMD.
CONCLUSIONS: Correlation of CRT und MI was high in DME and moderate in AMD. Future studies will examine if metamorphopsia measurement is a feasible tool for detection of conversion into neovascular AMD and for (self-)monitoring.
MATERIAL AND METHODS: Sixty-six eyes of 66 patients, DME: 19 (11 males, 8 females; age 42 - 76); AMD: 47 (13 male, 34 female; age 56 - 93) were included in this convenient sample study and classified as having or not having macular edema (central 500 µm, Cirrus HD-OCT). Best corrected monocular distance visual acuity (BCVA), Amsler Test, Metamorphopsia Index of AMD - A Metamorphopsia Detector, binocular ophthalmoscopy, central retinal thickness (SD-OCT) and fluorescein angiography, if necessary, were performed. Correlation of central retinal thickness and metamorphopsia index was evaluated by Spearman correlation.
RESULTS: Mean BCVA (logMAR) was 0.27 (SD 0.3) in DME and 0.29 (SD 0.2) in AMD. Spearman's rho as a measure for correlation between CRT and MI was 0.88 (p < 0.001) in DME and 0.56 (p < 0.001) in AMD.
CONCLUSIONS: Correlation of CRT und MI was high in DME and moderate in AMD. Future studies will examine if metamorphopsia measurement is a feasible tool for detection of conversion into neovascular AMD and for (self-)monitoring.