Necrobiosis Lipoidica Diabeticorum: A Rare and Difficult-to-Treat Condition.

Necrobiosis lipoidica (NL) is a chronic granulomatous dermatologic condition usually associated with diabetes mellitus (DM). Early diagnosis and treatment can improve the quality of life of the patient and prevent the development of squamous cell carcinoma. Treatment options include corticosteroids, tacrolimus, cyclosporine, fumaric acid esters, biologics (including adalimumab, etanercept, and infliximab), and phototherapy with varying degrees of success. Here, we report a case of NL diabeticorum, which was effectively treated with immunosuppressants and keratolytics.