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Войти в исследования Internal medicine (Tokyo, Japan) · 2001
Improvement of anti-Hu-associated paraneoplastic sensory neuropathy after chemoradiotherapy in a small cell lung cancer patient.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Suzuki M, Kimura H, Tachibana I, Fujimura H, Nakatsuji Y, Sugai F, Naba I, Nakamori M, Morishita H, Arai T, Osaki T, Hayashi S
Аннотация
A 66-year-old man developed progressive painful dysesthesia in his hands and feet over 3 months. His vibration sense was impaired and sensory nerve action potentials of the limbs were not evoked. Biopsy of the peroneal nerve revealed sensory neuropathy. Positive anti-Hu antibody facilitated delineation of a right hilar mass and a metastatic lymph node in thoracic CT scan. He was diagnosed as small cell lung cancer associated with paraneoplastic sensory neuropathy. A complete response was achieved through chemotherapy (carboplatin and etoposide) and subsequent radiation therapy. Notably, his neurological conditions, although not changed during the hospitalization, gradually improved afterwards.