[Research progress on the applicability of diagnostic criteria for metabolic and alcohol-related liver disease in patients with cirrhosis and after liver transplantation].

Metabolic and alcohol-related liver disease (MetALD) is a key subtype within the new classification system of fatty liver disease, and its diagnosis relies on three core elements: hepatic steatosis, metabolic dysfunction, and alcohol consumption. However, the applicability of current diagnostic criteria is limited in patients with cirrhosis and liver transplant recipients due to structural destruction of the liver, remodeling of metabolic status, and difficulties in accurately assessing alcohol intake. This article systematically reviews the current application of MetALD diagnostic criteria in the above special populations, focusing on the key limitations in clinical evaluation, and explores precision diagnostic strategies including combined biomarker detection and optimization of imaging techniques, aiming to provide a basis for stratified management and prognostic assessment in these patients.