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Current problems in cardiology · 2026

Clinical and echocardiographic predictors of reintervention after percutaneous or surgical treatment of rheumatic mitral stenosis: A systematic review.

СтатьяСистематический обзорНазвание и аннотация: Перевод в очереди
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Gómez-Gualdrón S A, Macias-Martinez J S, Pulido-Parra A M, Higuera-Leal S A, Vesga-Angarita B E

Аннотация

BACKGROUND: Rheumatic mitral stenosis remains an important cause of valvular heart disease worldwide. Although percutaneous and surgical interventions improve symptoms and hemodynamics, some patients develop restenosis, adverse events, or require repeat interventions during follow-up. Identifying clinical and echocardiographic factors associated with these outcomes is important for risk stratification.

METHODS: A systematic review was conducted following PRISMA guidelines to identify predictors of clinical outcomes after percutaneous or surgical treatment of rheumatic mitral stenosis. A search was performed in PubMed, PMC, Ovid MEDLINE, ScienceDirect, and Scopus without language or date restrictions. Studies evaluating clinical or echocardiographic predictors and reporting OR, HR, or RR were included. Study selection, data extraction, and risk of bias assessment were performed using the Newcastle-Ottawa Scale. Due to heterogeneity among studies, a qualitative synthesis was conducted.

RESULTS: Fourteen studies were included. The evaluated predictors mainly corresponded to clinical, echocardiographic, hemodynamic, and procedural variables. Some studies identified pulmonary hypertension, unfavorable valvular anatomy, and suboptimal hemodynamic results as factors associated with adverse events or reintervention. In contrast, achieving a post-procedural mitral valve area ≥2 cm² was associated with a lower risk of restenosis and cardiovascular events.

CONCLUSIONS: Clinical and echocardiographic characteristics influence outcomes after intervention for rheumatic mitral stenosis. Baseline valvular morphology and the immediate hemodynamic result of the procedure appear to be key determinants of prognosis and risk of reintervention.

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