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DOI 10.18632/aging.205165

Медицинская библиотека · Aging · 2023

Identification and diagnostic potential of serum microRNAs as biomarkers for early detection of Alzheimer's disease.

Han Ying-Hao, Xiang Hong-Yi, Lee Dong Hun, Feng Lin, Sun Hu-Nan, Jin Mei-Hua, Kwon Taeho

СтатьяПоддержка исследования: вне правительства СШАПеревод пока не подготовлен

Аннотация

INTRODUCTION

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with diverse symptoms and frequent comorbidities, posing diagnostic challenges. Despite advances in ASD awareness and diagnostic methods, significant knowledge gaps persist among healthcare professionals. This study assessed physicians' knowledge of ASD, focusing on symptoms, comorbidities, and diagnostic challenges to enhance patient care.

MATERIAL AND

METHODS

This study, conducted in 2024, involved physicians attending courses at the Center of Postgraduate Medical Education in Warsaw (CMKP). Participation was anonymous and voluntary. Respondents completed the author's own questionnaire and the Knowledge about Childhood Autism among Health Workers (KCAHW) questionnaire to assess autism knowledge across four domains: social interaction impairments, communication issues, obsessive behaviors, and disorder onset and comorbidities. Physicians also provided professional and demographic data.

RESULTS

The study included 395 physicians, primarily young (mean age: 31), female (75%), and in early career stages, with most having up to 5 years of experience. While 75% had some contact with individuals on the autism spectrum, only 28% had close family or acquaintances with ASD. Knowledge about autism was moderate, averaging 74% correct responses, with higher accuracy in recognizing social interaction impairments (80%) and repetitive behaviors (78.5%), but lower accuracy regarding comorbidities (63%). Younger, less experienced physicians, women, and those with personal ASD contact had higher knowledge about autism.

CONCLUSIONS

The study highlights the need for targeted ASD education to address specific knowledge gaps among healthcare professionals, essential for providing informed and compassionate care.

Для цитирования: Han Ying-Hao, Xiang Hong-Yi, Lee Dong Hun, Feng Lin, Sun Hu-Nan, Jin Mei-Hua, Kwon Taeho. Identification and diagnostic potential of serum microRNAs as biomarkers for early detection of Alzheimer's disease.. Aging. 2023. DOI: 10.18632/aging.205165.

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