American journal of otolaryngology · 2026
Obstructive sleep apnea and twins.
СтатьяКлинический случайСистематический обзорНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Ошибки и ограничения
История · было → стало
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Iannella Giannicola, Collettini Andrea, Polimeni Antonella, De Virgilio Armando, Mancini Patrizia, Pace Annalisa, Maniaci Antonino, Lechien Jerome R, Chiesa-Estomba Carlos-Miguel, Vaira Luigi A, Cocuzza Salvatore, Caranti Alberto, Vicini Claudio, Casale Manuele, Moffa Antonio, Bellizzi Mario Giuseppe, Croce Enrica, Nicoletti Saverio, Dispenza Francesco, Magliulo Giuseppe
Аннотация
PURPOSE: Present an intriguing case of a man suffering of OSA who has a homozygous monochorionic twin. Made a systematic review of the literature to summarize existing data and the reported incidence of OSA in twins.
METHODS: Case presentation and systematic literature review, according to the PRISMA guidelines about twins and Obstructive sleep Apnea.
RESULTS: Our patient had a severe OSA condition with an Apnea Hypopnea index (AHI) of 57.6. This patient had a twin who did not suffer from sleep apnea and presented different oropharyngeal and endoscopic anatomical characteristics. Six eligible studies were identified investigating OSA or OSA-related traits in twins. All studies demonstrated higher concordance among monozygotic than dizygotic twins and substantial heritability estimates (40%-83%), particularly for AHI and ODI. However, non-shared environmental and anatomical factors accounted for considerable phenotypic variability.
CONCLUSION: Despite the genetic factors related to the sleep apnea, differences in anatomical features and lifestyle could contributed to the different expression of OSA.
METHODS: Case presentation and systematic literature review, according to the PRISMA guidelines about twins and Obstructive sleep Apnea.
RESULTS: Our patient had a severe OSA condition with an Apnea Hypopnea index (AHI) of 57.6. This patient had a twin who did not suffer from sleep apnea and presented different oropharyngeal and endoscopic anatomical characteristics. Six eligible studies were identified investigating OSA or OSA-related traits in twins. All studies demonstrated higher concordance among monozygotic than dizygotic twins and substantial heritability estimates (40%-83%), particularly for AHI and ODI. However, non-shared environmental and anatomical factors accounted for considerable phenotypic variability.
CONCLUSION: Despite the genetic factors related to the sleep apnea, differences in anatomical features and lifestyle could contributed to the different expression of OSA.