Adverse granulomatous reaction after cosmetic dermal silicone injection.

BACKGROUND

Various alloplastic injectable implants have been developed for soft tissue augmentation without surgery, but different local or systemic adverse reactions have limited their use for cosmetic purposes.

OBJECTIVE

To examine the problems associated with silicone injection.

METHODS

Case report and literature review.

RESULTS

We describe an adverse granulomatous reaction after the injection of liquid silicone for lip augmentation, causing facial disfigurement. Although the initial response to steroids was poor, after 3 years of follow-up the nodules have almost disappeared spontaneously.

CONCLUSION

We advise that silicone injection be performed solely by trained physicians using medical-grade silicone or consider other injectable materials.