MedElevator
Войти в исследования The British journal of radiology · 2025
Evaluation of free-breathing, non-ECG-triggered magnetic resonance T1 mapping derived from multitasking imaging at 3.0 T in patients with ischaemic and non-ischaemic cardiomyopathy.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Wang Shiya, Xu Jingjing, Hua Yiying, Wang Yaqiong, Lu Hongfei, Sun Yi, Guo Jiajun, She Jiaqi, Ge Meiying, Zeng Mengsu, Chen Yinyin, Jin Hang
Аннотация
OBJECTIVE: To evaluate the image quality of the free-breathing, non-ECG-multitasking T1 mapping and to compare T1 values, lesion area, and ROC curve with those derived from the traditional MOLLI sequence in ischaemic and non-ischaemic cardiomyopathy.
METHODS: In vitro, T1 values from CMR multitasking and MOLLI images were compared in 4 phantoms. In vivo studies included 108 patients (38 ischaemic cardiomyopathy, 70 non-ischaemic cardiomyopathy) and 31 healthy volunteers. All underwent mid-ventricular short-axis CMR Multitasking (free-breathing) and MOLLI (breath-held). Image quality was scored (4-point scale). T1 values and lesion areas were compared via linear regression, Bland-Altman analysis, and ROC curves (LGE as reference).
RESULTS: Phantom T1 values showed excellent agreement (Multitasking versus reference: R2 = 0.99, P < .001). In vivo, multitasking strongly correlated with MOLLI for native T1 in healthy subjects (R2 = 0.69), ischaemic (R2 = 0.71), and non-ischaemic groups (R2 = 0.81, all P < .001). Multitasking demonstrated superior image quality in patients with breath-holding difficulties and adverse heart rates (P < .001). MOLLI image quality declined with breath-holding difficulties, arrhythmia, and high BMI (P < .05); multitasking was less affected but still impacted by BMI (P < .05). Lesion areas showed no inter-sequence differences (P > .05). ROC analysis revealed comparable diagnostic accuracy between sequences in stable patients (P > .05), but superior multitasking performance in breath-holding difficulties and arrhythmia subgroups (P < .05).
CONCLUSION: Multitasking provides accurate T1 quantification and lesion delineation in cardiomyopathy, with enhanced robustness for patients with poor breath-holding or arrhythmia. BMI-related limitations warrant technical refinement.
ADVANCES IN KNOWLEDGE: Free-breathing, non-ECG CMR multitasking achieves accurate T1 mapping in ischaemic/non-ischaemic cardiomyopathy, overcoming ECG/respiratory limitation.
METHODS: In vitro, T1 values from CMR multitasking and MOLLI images were compared in 4 phantoms. In vivo studies included 108 patients (38 ischaemic cardiomyopathy, 70 non-ischaemic cardiomyopathy) and 31 healthy volunteers. All underwent mid-ventricular short-axis CMR Multitasking (free-breathing) and MOLLI (breath-held). Image quality was scored (4-point scale). T1 values and lesion areas were compared via linear regression, Bland-Altman analysis, and ROC curves (LGE as reference).
RESULTS: Phantom T1 values showed excellent agreement (Multitasking versus reference: R2 = 0.99, P < .001). In vivo, multitasking strongly correlated with MOLLI for native T1 in healthy subjects (R2 = 0.69), ischaemic (R2 = 0.71), and non-ischaemic groups (R2 = 0.81, all P < .001). Multitasking demonstrated superior image quality in patients with breath-holding difficulties and adverse heart rates (P < .001). MOLLI image quality declined with breath-holding difficulties, arrhythmia, and high BMI (P < .05); multitasking was less affected but still impacted by BMI (P < .05). Lesion areas showed no inter-sequence differences (P > .05). ROC analysis revealed comparable diagnostic accuracy between sequences in stable patients (P > .05), but superior multitasking performance in breath-holding difficulties and arrhythmia subgroups (P < .05).
CONCLUSION: Multitasking provides accurate T1 quantification and lesion delineation in cardiomyopathy, with enhanced robustness for patients with poor breath-holding or arrhythmia. BMI-related limitations warrant technical refinement.
ADVANCES IN KNOWLEDGE: Free-breathing, non-ECG CMR multitasking achieves accurate T1 mapping in ischaemic/non-ischaemic cardiomyopathy, overcoming ECG/respiratory limitation.