MedElevator
Войти в исследования Ocular immunology and inflammation · 2012
Spectrum of Fuchs uveitic syndrome in a North Indian population.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Tandon Manjari, Malhotra Paavan Puneet, Gupta Vishali, Gupta Amod, Sharma Aman
Аннотация
PURPOSE: To describe patients with Fuchs uveitis syndrome (FUS) in North India.
DESIGN: Retrospective case series.
METHODS: One hundred ninety-eight eyes of 183 patients with FUS were reviewed at the Post Graduate Institute of Medical Education and Research, Advanced Eye Centre, Department of Ophthalmology, between December 1996 and September 2011. Demographic profile, clinical findings at presentation, risk of new complications, and rate of decreased vision were the main outcome measures.
RESULTS: The mean age at presentation was 30.1 ± 9.4 years. Male-to-female ratio was 1.1:1. Fifteen patients (8.1%) had bilateral involvement. Clinical findings at presentation included diffuse keratic precipitates (92.4%), anterior chamber cells (54.5%), diffuse iris atrophy without hypochromia (29.3%), heterochromia (24.7%), iris nodules (16.1%), cataract/pseudophakia (79.3%), vitreous cells (61.1%), elevated intraocular pressure (13.6%), and chorioretinal scars (2%). On fluorescein angiography, hyperfluorescence of the optic disc was detected in 28 of 51 eyes (55%), peripheral vasculitis in 1 (2%) and both in 8 eyes (15.7%). OCT showed traction papillopathy in 6 of 34 eyes (17.6%). None of the eyes showed cystoid macular edema.
CONCLUSION: Heterochromia is seen only in 25% of patients with Fuchsheterochromic uveitis in brown irides. Diffuse stellate keratic precipitates, low cellular reaction, vitritis, vitreous opacities, diffuse iris stromal atrophy in the absence of posterior synechia, and macular edema are other parameters helpful in diagnosing FUS.
DESIGN: Retrospective case series.
METHODS: One hundred ninety-eight eyes of 183 patients with FUS were reviewed at the Post Graduate Institute of Medical Education and Research, Advanced Eye Centre, Department of Ophthalmology, between December 1996 and September 2011. Demographic profile, clinical findings at presentation, risk of new complications, and rate of decreased vision were the main outcome measures.
RESULTS: The mean age at presentation was 30.1 ± 9.4 years. Male-to-female ratio was 1.1:1. Fifteen patients (8.1%) had bilateral involvement. Clinical findings at presentation included diffuse keratic precipitates (92.4%), anterior chamber cells (54.5%), diffuse iris atrophy without hypochromia (29.3%), heterochromia (24.7%), iris nodules (16.1%), cataract/pseudophakia (79.3%), vitreous cells (61.1%), elevated intraocular pressure (13.6%), and chorioretinal scars (2%). On fluorescein angiography, hyperfluorescence of the optic disc was detected in 28 of 51 eyes (55%), peripheral vasculitis in 1 (2%) and both in 8 eyes (15.7%). OCT showed traction papillopathy in 6 of 34 eyes (17.6%). None of the eyes showed cystoid macular edema.
CONCLUSION: Heterochromia is seen only in 25% of patients with Fuchsheterochromic uveitis in brown irides. Diffuse stellate keratic precipitates, low cellular reaction, vitritis, vitreous opacities, diffuse iris stromal atrophy in the absence of posterior synechia, and macular edema are other parameters helpful in diagnosing FUS.