DOI 10.1016/j.jaccas.2025.104752
Anesthetic Management in Combined Off-Pump CABG and EC-IC Bypass for CAD and Moyamoya Disease.
Аннотация
BACKGROUND
Surgical treatment of moyamoya disease combined with coronary heart disease presents unique anesthetic challenges.
CASE SUMMARY: A 56-year-old woman underwent combined off-pump coronary artery bypass grafting and extracranial-intracranial arterial bypass surgery. The challenges in this surgery included maintaining cerebral oxygenation (regional cerebral oxygen saturation: >75% of baseline), controlled heart rate (60-70 beats/min), lung-protective ventilation (partial arterial pressure of carbon dioxide: 40-45 mm Hg), and mean arterial pressure >70 mm Hg. The patient experienced 2 intraoperative emergencies: hypotension and cerebral oxygen desaturation. The first episode was caused by cardiac displacement and was managed with fluid resuscitation and norepinephrine. The second episode likely resulted from myocardial ischemia-reperfusion injury and was treated with inotropes and coronary vasodilators.
DISCUSSION: The key to anesthetic management in combined heart-brain surgery lies in balancing the heart-brain perfusion conflict while integrating cerebral function monitoring and myocardial protection.
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