Archivos espanoles de urologia · 2025
Case Report of Rare Metastasis of Renal Cell Carcinoma to the Bladder: A New Hypothesis and Literature Review.
СтатьяКлинический случайОбзорНазвание и аннотация: Перевод в очереди
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Manav Alper Nesip
Аннотация
INTRODUCTION: Metastatic renal cell carcinoma (RCC) to the bladder is extremely rare. A total of 1.6% of the patients were found via autopsy reports.
CASE PRESENTATION: A 44-year-old male patient presented with left flank pain and hematuria. A 40 mm tumor extending into the pelvis was detected in contrast-enhanced computed tomography (CECT). After benign urine cytology and transurethral-resection (TUR) biopsy from the bladder, left nephroureterectomy and ureteral cuff resection were performed because of a left endophytic renal mass and suspected upper tract urothelial carcinoma. Pathology analysis revealed papillary RCC. In the patient with hematuria, a 16mm mass was detected in the bladder 2 years after nephrectomy. Papillary type RCC was detected after complete TUR of the bladder tumor. Left iliac-lymph-node metastasis was detected via postoperative positron emission tomography-computed tomography (PET-CT). After six months of sunitinib treatment, the metastatic lymphadenopathy was found to regress on PET-CT.
DISCUSSION: Solitary resectable intravesical metastatic RCC is a good prognostic factor. Late-onset systemic metastasis may be observed and should be considered during follow-up. PET-CT scanning should be performed if necessary, and the patient can be treated with sunitinib.
CASE PRESENTATION: A 44-year-old male patient presented with left flank pain and hematuria. A 40 mm tumor extending into the pelvis was detected in contrast-enhanced computed tomography (CECT). After benign urine cytology and transurethral-resection (TUR) biopsy from the bladder, left nephroureterectomy and ureteral cuff resection were performed because of a left endophytic renal mass and suspected upper tract urothelial carcinoma. Pathology analysis revealed papillary RCC. In the patient with hematuria, a 16mm mass was detected in the bladder 2 years after nephrectomy. Papillary type RCC was detected after complete TUR of the bladder tumor. Left iliac-lymph-node metastasis was detected via postoperative positron emission tomography-computed tomography (PET-CT). After six months of sunitinib treatment, the metastatic lymphadenopathy was found to regress on PET-CT.
DISCUSSION: Solitary resectable intravesical metastatic RCC is a good prognostic factor. Late-onset systemic metastasis may be observed and should be considered during follow-up. PET-CT scanning should be performed if necessary, and the patient can be treated with sunitinib.