Effect of pyridoxine deficiency on rat intestinal alkaline phsophatase.

The effect of pyridoxine deficiency was studied on the intestinal alkaline phosphatase of rat. Different segments of the intestine differed in their response to pyridoxine deficiency. In the duodenum alkaline phosphatase activity was decreased, whereas it was markedly increased in the ileum and the jejunal enzyme was least affected. The electrophoretic pattern of isoenzymes of alkaline phosphatase was altered in the ileum of B6 deficient rats.