DNA methylation modification: Dawn of research on cornea-related diseases.

DNA methylation is a significant form of epigenetic modification that plays a crucial role in the occurrence and progression of diseases by regulating gene expression. Recent advancements in our understanding of DNA methylation have demonstrated its involvement in corneal damage repair and various corneal diseases. This article reviews the mechanisms and effects of DNA methylation modifications in corneal injury repair, keratoconus, corneal dystrophy, keratitis, and other related conditions. The aim is to enhance our understanding of the vital role of DNA methylation in the pathogenesis of corneal injuries and the development of cornea-related diseases. The phenomenon of DNA methylation in these conditions may offer new ideas and insights for therapeutic approaches.