Intestinal Failure (New York, N.Y.) · 2025
Cocoon Syndrome as a Cause of Intestinal Failure and Indication for Combined Liver-Intestine-Kidney Transplantation.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Gentilini M V, Doeyo M, Marco Santillán, Illidge P Lc, Pattin F, Fraile A, Ramisch D, Rumbo M, Solar H, Gondolesi G E
Аннотация
BACKGROUND: Cocoon Syndrome, or sclerosing encapsulating peritonitis, is a rare but severe complication of long-term peritoneal dialysis. It can lead to progressive fibrotic encapsulation of the intestines, causing intestinal obstruction due to a fibrous membrane encasing the abdominal organs.
CASE REPORT: We present a complex case of a 29-year-old male with history of nephronophthisis and four years on peritoneal dialysis who developed Cocoon Syndrome, leading to intestinal perforation and total enterectomy, resulting in irreversible intestinal failure. After prolonged dependence on parenteral nutrition, he developed intestinal failure-associated liver disease, ultimately becoming a candidate for combined liver-intestine and kidney transplantation.
CONCLUSION: This case illustrates how advanced Cocoon Syndrome can lead to severe and progressive complications that may ultimately require combined liver-intestine and kidney transplantation. It underscores the importance of early recognition and appropriate multidisciplinary management to improve patient outcomes.
CASE REPORT: We present a complex case of a 29-year-old male with history of nephronophthisis and four years on peritoneal dialysis who developed Cocoon Syndrome, leading to intestinal perforation and total enterectomy, resulting in irreversible intestinal failure. After prolonged dependence on parenteral nutrition, he developed intestinal failure-associated liver disease, ultimately becoming a candidate for combined liver-intestine and kidney transplantation.
CONCLUSION: This case illustrates how advanced Cocoon Syndrome can lead to severe and progressive complications that may ultimately require combined liver-intestine and kidney transplantation. It underscores the importance of early recognition and appropriate multidisciplinary management to improve patient outcomes.