Endocrinologia, diabetes y nutricion · 2026
Vitamin K in home parenteral nutrition: Is it really necessary?
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Diego Estrella, Farnández María Del Carmen, de León Beatriz, Monzón Andoni, Isasa Leire, Sordo Beatriz, Valdés Nuria
Аннотация
INTRODUCTION: Multivitamin preparations with added vitamin K in parenteral nutrition (PN) ensure the coverage of this micronutrient in all adults, as indicated by the latest ESPEN clinical practice guidelines on micronutrients.
OBJECTIVES: To monitor vitamin K levels after adding this multivitamin with vitamin K in patients requiring home parenteral nutrition (HPN) at Hospital Universitario Cruces (Bilbao, Basque County, Spain) from 2021 to 2022.
MATERIALS AND METHODS: We analyzed vitamin K levels were collected 6 months into therapy with the multivitamin containing vitamin K in home parenteral nutrition.
RESULTS: At our centre, a total of 8 patients required home parenteral nutrition due to intestinal failure type III, 60% of whom were men, with a mean age of 58±13 years. The cause of intestinal failure was short bowel syndrome (50%), intestinal mucosal disease (38%), and intestinal dysmotility (12%). After adding the multivitamin with vitamin K, 80% (6/8) of patients exhibited elevated vitamin K levels, with a mean of 4.4μl/L.
CONCLUSIONS: After observing vitamin K levels above the upper limit of normal, we reached consensus with the Pharmacy Service to discontinue this multivitamin and restart conventional multivitamin. After this initiative, the vitamin K levels of our patients normalized.
OBJECTIVES: To monitor vitamin K levels after adding this multivitamin with vitamin K in patients requiring home parenteral nutrition (HPN) at Hospital Universitario Cruces (Bilbao, Basque County, Spain) from 2021 to 2022.
MATERIALS AND METHODS: We analyzed vitamin K levels were collected 6 months into therapy with the multivitamin containing vitamin K in home parenteral nutrition.
RESULTS: At our centre, a total of 8 patients required home parenteral nutrition due to intestinal failure type III, 60% of whom were men, with a mean age of 58±13 years. The cause of intestinal failure was short bowel syndrome (50%), intestinal mucosal disease (38%), and intestinal dysmotility (12%). After adding the multivitamin with vitamin K, 80% (6/8) of patients exhibited elevated vitamin K levels, with a mean of 4.4μl/L.
CONCLUSIONS: After observing vitamin K levels above the upper limit of normal, we reached consensus with the Pharmacy Service to discontinue this multivitamin and restart conventional multivitamin. After this initiative, the vitamin K levels of our patients normalized.