Vascular Liver Disease: Emerging Concepts in the Sinusoidal Space.

Vascular liver pathology represents a heterogenous group of diseases impacted by the dual blood supply to the liver at each distinct microanatomic site. Portal vein-based disease is well described in association with portal vein thrombosis but may also precede or occur in the absence of thrombosis. Central vein-based disease is also well described in association with right heart failure and Budd Chiari syndrome but may show similar features with sinusoidal obstruction. Sinusoidal-based vascular disease is not as well characterized, and several emerging concepts are reviewed in this article.