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DOI 10.1002/cnm.3541

Медицинская библиотека · International journal for numerical methods in biomedical engineering · 2021

A finite element model to predict the consequences of endolymphatic hydrops in the basilar membrane.

Areias Bruno, Parente Marco P L, Gentil Fernanda, Caroça Cristina, Paço João, Natal Jorge Renato M

СтатьяПоддержка исследования: вне правительства СШАПеревод в очереди

Аннотация

Ménière's disease is an inner ear disorder, associated with episodes of vertigo, fluctuant hearing loss, tinnitus, and aural fullness. Ménière's disease is associated with endolymphatic hydrops. Clinical evidences show that this disease is often incapacitating, negatively affecting the patients' everyday life. The pathogenesis of Ménière's disease is still not fully understood and remains unclear. Previous numerical studies available in the literature related with endolymphatic hydrops, are very scarce. The present work applies the finite element method to investigate the consequences of endolymphatic hydrops in the normal hearing, associated with the Ménière's disease. The obtained results for the steady state dynamics analysis are in accordance with clinical evidences. The results show that the basilar membrane is not affected in the same intensity along its length and that the lower frequencies are more affected by the endolymphatic hydrops. From a clinical point of view, this work shows the relationship between the increasing of the endolymphatic pressure and the development of hearing loss.

Для цитирования: Areias Bruno, Parente Marco P L, Gentil Fernanda, Caroça Cristina, Paço João, Natal Jorge Renato M. A finite element model to predict the consequences of endolymphatic hydrops in the basilar membrane.. International journal for numerical methods in biomedical engineering. 2021. DOI: 10.1002/cnm.3541.

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