Isolated Gallbladder Tuberculosis Mimicking Chronic Cholecystitis: A Case Report.

Isolated gallbladder tuberculosis (GBTB) is a rare disease, even in endemic areas, and is often misdiagnosed due to its nonspecific clinical and imaging findings. Histopathological evaluation, demonstrating granulomatous inflammation with caseous necrosis, remains the only definitive method of diagnosis. Thus, maintaining a high index of suspicion and routine histological assessment of resected specimens are vital for its timely management, especially in patients with a history of tuberculosis. We report a similar case in a 50-year-old male patient with imaging suggestive of gallbladder perforation and chronic cholecystitis, which later revealed a cryptic GBTB dug up during histopathological examination.