Spontaneous closure of macular hole in a patient with toxoplasma retinochoroiditis.

We report a unique case of a man in his early 60s, diagnosed with systemic lupus erythematosus and on immunosuppressive therapy. He developed bilateral toxoplasma retinochoroiditis and subsequently experienced the spontaneous closure of a full-thickness macular hole in his left eye following treatment. Following combined therapy (intravitreal clindamycin, dexamethasone injection, and systemic oral trimethoprim and sulfamethoxazole along with oral steroids), the patient showed significant improvement, with best corrected visual acuity increasing from 2/60 in both eyes to 6/9;N8 in the right eye and 6/60;N18 in the left eye at the final follow-up.