European heart journal. Case reports · 2026
Cardiac resynchronisation therapy in dextrocardia with situs Inversus totalis: a case report of strategies and outcomes in bipolar lead-based devices.
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Khasnavis Sujoy, Saouma Samer, Grushko Michael, Gross Jay
Аннотация
BACKGROUND: Cardiac resynchronisation therapy pacemaker (CRT-P) placement and coronary sinus cannulation (CSC) are notably challenging in dextrocardia (DXC).
CASE SUMMARY: A 56-year-old female with a diagnosis of DXC, sick sinus syndrome (SSS), paroxysmal atrial fibrillation (pAF), and heart failure reduced ejection fraction (HFrEF) presented for symptoms with exertion. Electrocardiogram (ECG) showed prolonged QRS necessitating CRT-P and CSC with right sided multipolar catheter and a bipolar lead. Postoperatively, there was improvement in QRS, EF, and symptoms.
DISCUSSION: CRT-P and CSC techniques in levocardia are well established. DXC requires unconventional CRT-P strategies. A right-sided multipolar catheter is valuable for CSC in DXC. This DXC case utilized a right-sided electrophysiology catheter and a bipolar coronary sinus (CS) lead. The use of these devices ensured that if the prior right ventricular (RV) ICD lead failed, a standard high S1 lead would be compatible with pacemaker headers.
TAKE HOME MESSAGE: A right-sided CSC system is useful for implanting CS leads with a left-sided device in DXC. While it comes at the expense of losing different pacing vectors, a bipolar CS lead is essential if there is a risk that the pre-existing bipolar RV lead will fail.
CASE SUMMARY: A 56-year-old female with a diagnosis of DXC, sick sinus syndrome (SSS), paroxysmal atrial fibrillation (pAF), and heart failure reduced ejection fraction (HFrEF) presented for symptoms with exertion. Electrocardiogram (ECG) showed prolonged QRS necessitating CRT-P and CSC with right sided multipolar catheter and a bipolar lead. Postoperatively, there was improvement in QRS, EF, and symptoms.
DISCUSSION: CRT-P and CSC techniques in levocardia are well established. DXC requires unconventional CRT-P strategies. A right-sided multipolar catheter is valuable for CSC in DXC. This DXC case utilized a right-sided electrophysiology catheter and a bipolar coronary sinus (CS) lead. The use of these devices ensured that if the prior right ventricular (RV) ICD lead failed, a standard high S1 lead would be compatible with pacemaker headers.
TAKE HOME MESSAGE: A right-sided CSC system is useful for implanting CS leads with a left-sided device in DXC. While it comes at the expense of losing different pacing vectors, a bipolar CS lead is essential if there is a risk that the pre-existing bipolar RV lead will fail.