Solitary plasmacytoma of the skull compressing the superior sagittal sinus: Case report and literature review.

INTRODUCTION

Solitary plasmacytomas are rare, localized plasma cell neoplasms without systemic involvement. Intracranial manifestations, particularly those compressing the superior sagittal sinus, are exceptionally uncommon and can mimic more common dural-based lesions such as meningiomas.

RESEARCH QUESTION: This study aims to highlight the diagnostic and therapeutic considerations in cases of intracranial solitary plasmacytoma involving superior sagittal sinus compression through a clinical case and a targeted literature review.

MATERIAL AND

METHODS

We report a case of a 52-year-old male who presented with progressive skull swelling as the only symptom. Due to the lesion's pronounced mass effect and marked compression of the superior sagittal sinus, a craniotomy and complete surgical resection were performed. A systematic literature search was conducted via PubMed to identify previously reported cases of intracranial solitary plasmacytoma involving superior sagittal sinus compression.

RESULTS

In the present case, histopathological examination confirmed the diagnosis of solitary plasmacytoma and surgical resection alone resulted in a favorable clinical outcome without recurrence during a 40-month follow-up. Our systematic review identified 14 patients with intracranial solitary plasmacytoma causing superior sagittal sinus compression across 12 published articles.

DISCUSSION AND

CONCLUSION

Differentiation from more common intracranial lesions is crucial and relies on careful radiologic and histopathologic evaluation. Solitary plasmacytoma should be considered in the differential diagnosis of dural-based lesions involving venous sinuses. Further studies and clinical reports are essential to clarify prognostic factors and to refine therapeutic strategies for this rare entity.