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DOI 10.1007/s00134-024-07341-7

Медицинская библиотека · Intensive care medicine · 2024

Invasive Fungal Diseases in Adult Patients in Intensive Care Unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM.

Bassetti Matteo, Giacobbe Daniele R, Agvald-Ohman Christina, Akova Murat, Alastruey-Izquierdo Ana, Arikan-Akdagli Sevtap, Azoulay Elie, Blot Stijn, Cornely Oliver A, Cuenca-Estrella Manuel, de Lange Dylan W, De Rosa Francesco G, De Waele Jan J, Dimopoulos George, Garnacho-Montero Jose, Hoenigl Martin, Kanj Souha S, Koehler Philipp, Kullberg Bart J, Lamoth Frédéric, Lass-Flörl Cornelia, Maertens Johan, Martin-Loeches Ignacio, Muñoz Patricia, Poulakou Garyphallia, Rello Jordi, Sanguinetti Maurizio, Taccone Fabio S, Timsit Jean-François, Torres Antoni, Vazquez Jose A, Wauters Joost, Asperges Erika, Cortegiani Andrea, Grecchi Cecilia, Karaiskos Ilias, Le Bihan Clément, Mercier Toine, Mortensen Klaus L, Peghin Maddalena, Rebuffi Chiara, Tejada Sofia, Vena Antonio, Zuccaro Valentina, Scudeller Luigia, Calandra Thierry, Study Group for Infections in Critically Ill Patients of the European Society of Clinical Microbiology and Infectious Diseases (ESGCIP), the Fungal Infection Study Group of the European Society of Clinical Microbiology and Infectious Diseases (EFISG), the European Society of Intensive Care Medicine (ESICM), the European Confederation of Medical Mycology (ECMM), the Mycoses Study Group Education and Research Consortium (MSGERC), the International Society of Antimicrobial Chemotherapy (ISAC), the International Society for Human and Animal Mycology (ISHAM), the Austrian Society for Medical Mycology (ÖGMM), the Italian Society of Anesthesia, Analgesia, Reanimation, and Intensive Care (SIAARTI), the Italian Society of Anti-Infective Therapy (SITA), and the FUNDICU Collaborators

СтатьяConsensus StatementПоддержка исследования: вне правительства СШАПеревод в очереди

Аннотация

PURPOSE: The aim of this document was to develop standardized research definitions of invasive fungal diseases (IFD) in non-neutropenic, adult patients without classical host factors for IFD, admitted to intensive care units (ICUs).

METHODS

After a systematic assessment of the diagnostic performance for IFD in the target population of already existing definitions and laboratory tests, consensus definitions were developed by a panel of experts using the RAND/UCLA appropriateness method.

RESULTS

Standardized research definitions were developed for proven invasive candidiasis, probable deep-seated candidiasis, proven invasive aspergillosis, probable invasive pulmonary aspergillosis, and probable tracheobronchial aspergillosis. The limited evidence on the performance of existing definitions and laboratory tests for the diagnosis of IFD other than candidiasis and aspergillosis precluded the development of dedicated definitions, at least pending further data. The standardized definitions provided in the present document are aimed to speed-up the design, and increase the feasibility, of future comparative research studies.

Для цитирования: Bassetti Matteo, Giacobbe Daniele R, Agvald-Ohman Christina, Akova Murat, Alastruey-Izquierdo Ana, Arikan-Akdagli Sevtap, Azoulay Elie, Blot Stijn, Cornely Oliver A, Cuenca-Estrella Manuel, de Lange Dylan W, De Rosa Francesco G, De Waele Jan J, Dimopoulos George, Garnacho-Montero Jose, Hoenigl Martin, Kanj Souha S, Koehler Philipp, Kullberg Bart J, Lamoth Frédéric, Lass-Flörl Cornelia, Maertens Johan, Martin-Loeches Ignacio, Muñoz Patricia, Poulakou Garyphallia, Rello Jordi, Sanguinetti Maurizio, Taccone Fabio S, Timsit Jean-François, Torres Antoni, Vazquez Jose A, Wauters Joost, Asperges Erika, Cortegiani Andrea, Grecchi Cecilia, Karaiskos Ilias, Le Bihan Clément, Mercier Toine, Mortensen Klaus L, Peghin Maddalena, Rebuffi Chiara, Tejada Sofia, Vena Antonio, Zuccaro Valentina, Scudeller Luigia, Calandra Thierry, Study Group for Infections in Critically Ill Patients of the European Society of Clinical Microbiology and Infectious Diseases (ESGCIP), the Fungal Infection Study Group of the European Society of Clinical Microbiology and Infectious Diseases (EFISG), the European Society of Intensive Care Medicine (ESICM), the European Confederation of Medical Mycology (ECMM), the Mycoses Study Group Education and Research Consortium (MSGERC), the International Society of Antimicrobial Chemotherapy (ISAC), the International Society for Human and Animal Mycology (ISHAM), the Austrian Society for Medical Mycology (ÖGMM), the Italian Society of Anesthesia, Analgesia, Reanimation, and Intensive Care (SIAARTI), the Italian Society of Anti-Infective Therapy (SITA), and the FUNDICU Collaborators. Invasive Fungal Diseases in Adult Patients in Intensive Care Unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM.. Intensive care medicine. 2024. DOI: 10.1007/s00134-024-07341-7.

Предметные рубрики MeSH

AdultHumansInvasive Fungal InfectionsAspergillosisCandidiasis, InvasiveIntensive Care Units
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