14th International Congress IAOP/AAOMP Clinical Pathology Conference Case 6.

The clinicopathologic features of oral cryptococcosis manifested as multifocal tumor-like lesions located in the upper and lower gingival tissues of a 36-year-old male patient with AIDS are described. The gingival lesions were the initial manifestation of disseminated cryptococcosis from which central nervous system involvement was established. Clinical differential diagnosis and histopathologic features are discussed. Effect of treatment on the gingival lesions after 18 months follow-up is presented.