Journal of vascular and interventional radiology : JVIR · 2026
Single-Session Outpatient Gallstone Organ-Sparing Cholangioscopy and Percutaneous Extraction (GO-SCOPE) for Symptomatic Biliary Colic: A Single-Center Retrospective Study.
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Smirniotopoulos John, Jain Neil, Kim Emily, Abouassaly Chadi, Trankiem Christine, Marchalik Daniel
Аннотация
PURPOSE: To test the hypothesis that gallstone organ-sparing cholangioscopy and percutaneous extraction (GO-SCOPE) achieves high single-session technical success, durable symptom improvement, and an acceptable safety profile in patients with symptomatic calculous biliary colic who elect nonsurgical management despite eligibility for cholecystectomy.
MATERIALS AND METHODS: This retrospective study evaluated consecutive patients who underwent GO-SCOPE between April 2024 and July 2025 at a single tertiary academic center. The procedure consisted of same-day percutaneous gallbladder access, cholangioscopy-assisted gallstone extraction with lithotripsy as needed, and placement of a percutaneous cholecystostomy or transcystic biliary drain for tract maturation. Sixty-six patients (mean age, 46.0 years; range, 25-72 years) underwent GO-SCOPE. Primary outcomes included technical success (removal of all visualized gallstones in a single session), clinical success (improvement or resolution of biliary colic symptoms), and 30-day adverse events classified according to the Society of Interventional Radiology (SIR) adverse event classification system. Secondary outcomes included residual or recurrent gallstones on follow-up imaging.
RESULTS: Single-session technical success was achieved in 60 (90.9%) of 66 patients; 6 required repeat cholangioscopy for residual stones. Mean time to tube removal was 21.3 days. Among 60 patients with 3-month follow-up imaging, 2 (3.3%) demonstrated asymptomatic subcentimeter gallstones. Clinical success was achieved in 59 (98.3%) of 60 patients at 3-month follow-up and 30 (96.8%) of 31 patients at 12-month follow-up. Four adverse events occurred, including 1 moderate and 3 severe.
CONCLUSIONS: GO-SCOPE demonstrated high technical and clinical success with an acceptable safety profile as an organ-sparing alternative to cholecystectomy in patients with symptomatic gallstone disease.
MATERIALS AND METHODS: This retrospective study evaluated consecutive patients who underwent GO-SCOPE between April 2024 and July 2025 at a single tertiary academic center. The procedure consisted of same-day percutaneous gallbladder access, cholangioscopy-assisted gallstone extraction with lithotripsy as needed, and placement of a percutaneous cholecystostomy or transcystic biliary drain for tract maturation. Sixty-six patients (mean age, 46.0 years; range, 25-72 years) underwent GO-SCOPE. Primary outcomes included technical success (removal of all visualized gallstones in a single session), clinical success (improvement or resolution of biliary colic symptoms), and 30-day adverse events classified according to the Society of Interventional Radiology (SIR) adverse event classification system. Secondary outcomes included residual or recurrent gallstones on follow-up imaging.
RESULTS: Single-session technical success was achieved in 60 (90.9%) of 66 patients; 6 required repeat cholangioscopy for residual stones. Mean time to tube removal was 21.3 days. Among 60 patients with 3-month follow-up imaging, 2 (3.3%) demonstrated asymptomatic subcentimeter gallstones. Clinical success was achieved in 59 (98.3%) of 60 patients at 3-month follow-up and 30 (96.8%) of 31 patients at 12-month follow-up. Four adverse events occurred, including 1 moderate and 3 severe.
CONCLUSIONS: GO-SCOPE demonstrated high technical and clinical success with an acceptable safety profile as an organ-sparing alternative to cholecystectomy in patients with symptomatic gallstone disease.