Gastrointestinal involvement in metastatic melanoma.

This case report details two instances of gastrointestinal (GI) involvement in metastatic melanoma. The first patient, a man in his mid-70s with a history of melanoma and recent brain metastases, presented with melaena and was found to have metastatic lesions in the stomach and duodenum. The second patient, a man in his late 50s with a history of chest wall melanoma, presented with complex GI symptoms and was discovered to have a metastatic melanoma lesion at the gastro-oesophageal junction. Both cases highlight the importance of maintaining a high degree of suspicion for GI metastasis from melanoma in patients presenting with GI symptoms, emphasising timely endoscopic evaluation and biopsy for accurate diagnosis and management.